Coal and Mineral Mass Fractions in Personal Respirable Dust Samples Collected by Central Appalachian Miners (bb26fbea-d871-46a4-9be0-6020a2aa0dd6)

"Coal Worker’s Pneumoconiosis (CWP) is an occupational lung disease caused by chronic exposure to respirable mine dust. After decades of steady decline, CWP incidence appears to be on the rise since the mid-1990s, particularly in some regions of Appalachia. Alarmingly, many of these cases have rapidly progressed to the most advanced form of CWP, referred to as Progressive Massive Fibrosis (PMF). Most of what is currently understood about respirable mine dust has been gleaned from routine regulatory monitoring, which tracks total mass concentration of respirable dust (mg/m3) and, less frequently, silica mass content. This paper focuses on the use of thermogravimetric analysis (TGA) as a way to provide basic characterization of the whole composition of the dust, allowing it to be classified into three mass fractions – coal, carbonate, and non-carbonate minerals. TGA was conducted on 59 dust samples collected by miners from eight coal mines in central Appalachia, and the results are discussed in terms of differences between mines, regions, and primary occupations. Consistent with prior results on area dust samples from some of the same mines, results of the personal samples generally show that the coal mass fraction of the dust is relatively low. Carbonate and non-carbonate minerals thus tend to make up the bulk of the dust mass, and vary across occupations and specific mines. INTRODUCTION After nearly four decades of decline, the prevalence of Coal Workers’ Pneumoconiosis (CWP, or “black lung”) in the US has been on the rise since the mid-1990s (Laney et al., 2014; Laney et al., 2010; Suarthana et al., 2011; Pollock et al., 2010; Antao et al., 2005; Blackley et al., 2016). Particularly alarming is the number of cases of progressive massive fibrosis (PMF), which is the most advanced form of the disease (Pollock et al., 2010; Antao et al., 2005; Blackley et al., 2016; Laney et al., 2017). A recent study by Laney et al. (2017) observed 192 US coal miners participating in the Coal Workers’ Health Surveillance Program (CWHSP) who had been diagnosed with PMF since 2000. Of the 163 (85%) that had a normal radiograph on file to use as a baseline, 27 (17%) of these individuals had progressed from a normal radiograph to PMF diagnosis in less than 10 years. Moreover, 162 (84%) of the individuals in that study worked in KY, WV or VA, and 169 (88%) had only ever mined underground. Blackley et al. (2016) also reported on a group of 60 PMF cases that were discovered by a single black lung clinic in eastern KY. Since seeking care at such clinics and participation in the CWHSP are voluntary, and could be influenced by a number of factors, these recent reports may well overestimate the degree of resurgence in severe disease (i.e., versus disease that was previously under-reported). Even so, they highlight a critical need to better understand the cause(s) of disease development and progression – such that effective interventions can be devised."