Response Surface Method Optimization to Improve Copper Extraction from Refractory Copper Oxide Ore

In this study, response surface methodology (RSM) and Box-Behnken design to improve copper extraction from refractory copper oxide ore were investigated. Based on single factor tests, quadratic polynomial equation to describe the relationship between influencing factors (particle size, leaching temperature, sulfuric acid concentration, leaching time) and copper leaching rate could be obtained by RSM. The optimum parameters determined by the model are as follows: particle size 64.60% − 74 μm, leaching temperature 74.15 °C, sulfuric acid concentration 0.49 mol/L, and leaching time 140.85 min. Under these conditions, experimental copper leaching rate of 85.12% could be achieved, which was very close to the predicted maximum value (85.34%) by the model, indicating the quadratic polynomial model was accurate and reliable. Copper leaching rate increased approximately by five percentage points comparing to the result of single factor tests. This study indicates that response surface methodology is an effective method to optimize experiment conditions and achieve an ideal experiment result.