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By Finney, W. R.

MUCH has been said and written of the "Big Inch," of the terrific obstacles encountered in its construction, of the colorful and tough men engaged in its building, but little has been publicized of the engineering and economic problems behind the scenes. Long before Pearl Harbor it was apparent to the petroleum industry that a critical oil shortage could be expected along the Atlantic seaboard, owing to delay in tanker deliveries as a result of convoy movements, and to allocation of vessels for foreign shipments. This area, with a normal consumption of approximately 1,800,000 barrels per day of oil and products, was almost entirely supplied by tanker. Pipe lines supplied an average of only 20,000 barrels per day in 1939, 40,300 barrels per day in 1940, and 55,000 barrels per day in 1941. A small amount of oil and products was also delivered via barge.

Jan 1, 1943

By József Faitli, Imre Gombköto, Barnabás Csoke, Tamás Magyar, Beáta Oláh, Sándor Nagy

"Raw materials are among the main building blocks of a growing economy. Without raw materials, no matter whether it is primary or secondary, production is not possible. Products with high added value require special materials. Recently, worldwide production of some important raw materials mainly comes from a handful of countries, for example: China (Rare Earths Elements (REE)), Russia, South Africa (Platinum Group Elements (PGE)), Democratic Republic of Congo (Cobalt), etc. In the EU as well as in Hungary, the importance of the so called 14 critical raw materials has been recognized. Within the frame of the TÁMOP-4.2.2.A-11/1/KONV-2012-0005 - CriticEL project, the Institute of Raw Materials Preparation and Environmental Processing in cooperation with the Institute of Mineralogy and Geology of the University of Miskolc are working on the exploration of the primary and secondary sources and developing innovative preparation technologies of critical raw materials in Hungary. The research work showed in this article, focused on the recovery of critical materials from LCD TVs and monitors. There are high deviations in different literatures regarding to concentrations of critical elements in displays (e.g.: indium), probably because of the differences in production year, producers and recovery technologies. During the research - described in this study - a well specified sample of quite large amount of displays had been used. The exact place and shape of the ITO (indium-tin oxide) layer were determined by SEM analysis. The applied preparation technology was developed based on the results of our investigations and by technologies found in the literature. The developed process accomplishes two main parts: the mechanical preparation (mainly the liberation of different display layers, removal of liquid crystal) and the acidic dissolution of indium."

Jan 1, 2014

By A. R. Laplante

A novel methodology to estimate gold recovery by gravity is presented. The methodology makes use of a population balance model which represents gold liberation, breakage and classification behaviour and applies pre-concentration and recovery performance curves to gravity-recoverable gold to predict overall recovery. Derivation of the necessary parameters is explained and demonstrated using data from an actual gravity circuit and one projected application. The methodology makes it possible to estimate the performance of circuits with large gold circulating loads and relatively low unit recoveries (e.g. jigs), or with high recoveries on a bleed of the circulating load (e.g. Knelson concentrators).

Jan 1, 1994

By J. S. Stewart

THIS paper was prompted by a persistent demand for what information we have that will throw light on the oil and gas possibilities of the Maritime Provinces. The problems involved were made familiar to the writer during three seasons of field work in New Brunswick and Nova Scotia. The reasons for renewed interest are: (1) In many parts of that region, the surface is underlain by a thick series of unaltered sedimentary rocks. (2) Oil seepages occur, and oil in commercial quantity has been exploited' near Moncton, New Brunswick, for many years. (3) In recent years, a new method of attack has been developed toward the finding of stratigraphic traps. This method is based on a detailed study of the geological history of the region, as revealed in surface outcrops and samples from deep wells. The well samples show the lateral variation of strata, far from any possible surface outcrop of the same beds. Sufficient work has now been done in the Maritime Provinces to reveal the broad features of the geological history and the character and distribution of the various rock formations. Comparatively little deep drilling has been done in this region, but the holes are widely scattered and the samples from them have added much to the information obtained from the numerous outcrops of bed-rock. The following discussion gives a summary of available information that has a bearing on the subject.

Jan 1, 1943

By C. E. Jordan

Under its program of advancing minerals technology, the Federal Bureau of Mines has developed a laboratory apparatus for continuous separation of minerals according to their dielectric properties. The unit consists of a rotating wire grid drum electrode and a fixed curved wire screen electrode positioned 3 mm apart. By applying high voltage across the electrodes, which are immersed in a dielectric fluid medium, a high-gradient electric field is produced. The high-dielectric-constant minerals are attracted and conveyed through the separator by the rotating drum electrode, whereas the low-dielectric-constant minerals settle through the fixed electrode. In typical tests, a sample of Montana chromite ore containing 43 percent chromite was concentrated to 72 percent chromite with 90 percent recovery.

Jan 1, 1977

By Philip W. Holland

This U.S. Bureau of Mines (USBM) report describes a chromatographic method that is used for rapid field determinations of carbon dioxide in natural gas streams at a USBM helium production facility. The method employs a commercially available portable gas chromatograph that is equipped with a 10-m fused-silica capillary column coated with a porous polymer. The instrument operating parameters permit determinations to be performed over a concentration range of 10 ppm to 10 pct with a frequency of 20 samples/h. The speed at which determinations can be performed is an important factor when evaluating efficiency or troubleshooting processes at the helium facility.

Jan 1, 1994

By C. Igathinathane

Coal is the most widely used fossil fuel in the world, providing more than 25% of world?s electrical power. Since, the behavior of coal particles in crushing and grinding circuits, concentration operations, and solid-liquid separations is strongly dependent on size, a reliable and accurate measurement of particle size and particle size distribution (PSD) is a vital aspect in coal cleaning. This paper presents a method for the characterization of ground coal particles using image analysis. We utilized a machine vision (MV) approach that used a document scanner as the imaging device and a user-coded ImageJ plug-in that processed the image and automated the PSD analysis and output results in textual and graphical forms. This approach used a sum of volumes (SVolume) as weighting factor for particle length as the primary dimension of analysis and was successfully applied to ground coal. The plug-in was further improved for computational performance in this study. Mechanical sieving (MS) was also used to compare the MV results. MV results showed that the PSD of ground coal followed a uni-modal normal distribution, and the log-normal plot against particle size exhibited a linear trend for most of the range. MS results, however, had three linear segments, when the width-based sieving results were transformed to lengths by applying the shape factor (width/length), but a definite deviation between the PSD plots was observed. This study demonstrates successful application of the MV SVolume approach for PSD analysis of ground coal, which can be extended to similar particulate minerals and products. Keywords: dimension, fiji, image j, image analysis, coal, particle size, plug-in

Sep 1, 2012

By R. W. Raymond

On the Manchuria. SOMEWHAT fatigued with excess of enjoyment and strenuous continuity of movement on the trip to and through California, the members and guests of the Institute party embarked Tuesday, Oct. 17, on the Pacific Mail S. S. Manchuria for a further journey to and through Japan. The good ship displayed the flag of the Institute (blue cross-hammers on a white ground), together with the Stars and Stripes and the ensign of the company. Uninterrupted fair weather and smooth water attended the passage to Honolulu. The Manchuria proved herself most commodious, comfortable and clean ("A sweeter steamship never sailed," quoth President Hunt) ; Captain Dixon and his officers were most agreeable, as well as most efficient; the passenger list comprised many congenial people besides ourselves-among them a score of missionary folk, and also Mr. M. H. de Young, Vice-President of the Panama

Jan 1, 1912

By Nadia C. Miller

In situ stope leaching is an innovative mining system that reduces the surface impacts of conventional underground mining. As in any leaching operation, stope leaching requires hydrologic site characterization and control of leaching solutions. Several tracer tests, using sodium chloride (NaCl) in various concentrations, were conducted by the U.S. Bureau of Mines (USBM) in an underground experimental stope to simulate a leaching environment. The tests were conducted in fractured crystalline rock that was partially water-saturated. As tests progressed, the surrounding fractures became more saturated. A predominant flow direction away from the stope was found during testing. Testing procedures, results, and a remediation plan for in situ leaching based on field observations are presented in this report.

Jan 1, 2010

By A. B. Hooker, L. C. IlsLey

"The last previous Bureau of Mines publication relative to details of permissible electric mine lamps is Bulletin 332, which describes 16 lamps approved prior to May 1930. Some of the lamps have become obsolete through the development of improved models which, with several new types, make it desirable to supplement the Bureau's published data relative to permissible electric mine lamps.In the following descriptions, lamps approved since May 1930 and prior to July 1, 1935, are placed in the three following groups: (1) Electric cap lamps, (2) electric hand lamps, and (3) lamps for miscellaneous applications,ELECTRIC CAP LAMPS APPROVED UNDER SCHEDULE 6B1. Edison model J lamp, approval no. 24. - The features that distinguish this lamp from earlier models of Edison electric cap lamps are:(a) The battery consists of two F-2 cells of square cross section and about 1-1/4 inches higher than M-14 cells in the model H lamp, making the battery narrower and higher than any of the earlier models of Edison cap lamps.(b) The cells are insulated from each other and the Monel-metal casing by enclosure in vulcanized-rubber baglike enclosures. Both cell terminals are insulated from the cell jar.(c) The battery is equipped with rubber-tube Bunsen-valve-type gas vents.(d) The battery casing is secured by a new-type magnetic lock.(e.) The battery and cover terminal clips have been redesigned to give a wiping contact."

Jun 1, 1936

By Raymond F. Moran

The history and development of the FMC Coke process has been reported in numerous presentations over the past 10 years (1, 2, 3, 4, 5, 6) but a short review is desirable, especially regarding the aspects that are influenced by the coal to be used. F'MC has been developing this process in pilot facilities since 1956 and in a modest sized plant in Kemmerer, Wyoming since 1960 (Figure I). This plant produces strong uniformly sized coke briquettes from a completely non-coking coal, namely Elkol, a sub-bituminous coal of the Adaville seam. Since operating commercially, over 300,000 tons have been produced, 90% of which has been used in electric phosphorus furnaces and some 10% of which went for trials in iron blast furnaces. We believe that this commercial use of non-coking coals is a unique experience in the history of coke manufacture.

Jan 1, 1975

By H Ishikawa, S Palaniandy

The gravity-induced stirred mill such as the TowerMill is an energy-efficient grinding solution used in secondary, tertiary, and regrinding duties in the mineral processing concentrator. The interest in this technology is emerging, with more than 300 mills installed globally in various grinding duties and commodities for the last 30 years. Although the technology is matured, there are still opportunities for improvement and the development of new knowledge to improve its circuit energy efficiency and reduce water consumption. Recent studies show that a combination of stress intensity, ore hardness, slurry density, and mill feed configuration can be used to evaluate the performance of the grinding circuit. A recent pilot-scale TowerMill test work at various stress intensities shows that a lower operating work index and size-specific energy were achieved at higher agitator tip speed and using medium size grinding media. These outcomes were confirmed through several site trials. A smaller 17 mm grinding media has reduced the operating work index and size-specific energy by 18 per cent and 11 per cent, respectively, compared to the 20 mm in a magnetite concentrator. Moreover, the conversion from top feed to bottom feed configuration has reduced the operating work index and size-specific energy by 13 per cent and 37 per cent, respectively. The circulating load was reduced by 34–38 per cent, leading to a reduction in the dilution water consumption in the hydrocyclone feed sump by 20 per cent. A variable frequency drive offers flexibility to change the stress intensities on the TowerMill, where a 35 per cent reduction in specific energy was achieved when the ore became soft. This paper explores the potential design and operating strategies that can be implemented to enhance the energy efficiency, reduce water consumption and reduce CO2 emissions in the circuit and finally evaluate its impact on the total cost of ownership.

Aug 24, 2022

By A. Deneys

An experimental technique has been devised for studying the reaction kinetics of the reaction: ZnO + 2Fe0 = Zn(g) + Fe203, by which zinc evolution can occur from a molten slag bath in the absence of a carbonaceous reductant. When studying the reaction kinetics by heating from room temperature, solid state reactions and poorly defined melting points may obscure the starting point of the reaction. In order to eliminate this problem, an experimental technique was devised whereby two molten slags could be melted independently, and then mixed, to provide a well defined starting point from which to begin taking measurements. Two crucibles were mounted in a vertical reaction cylinder. The upper, mild steel, crucible had a bottom pouring plug which was sealed by a steel stopper rod. A fayalite mixture was contained in this crucible. The lower crucible contained an A12O3-CaO-SiO2-ZnO solution. Once the two slags had been melted, the steel stopper rod was removed from the upper crucible. The upper, reduced slag (fayalite in equilibrium with the upper steel crucible), drained into the lower crucible where the two slags were mixed by submerged argon stirring. Dip samples were taken to measure the zinc content of the final mixture as a function of time. The experimental procedure will be described, as well as results of experiments which were conducted on synthetic slags. The system investigated was similar to the lead blast furnace slag which is produced by the primary lead smelters of Missouri, USA.

Jan 1, 1997

By O. D. Gonzalez, R. A. Oriani

A thermo-osmosis technique has been used to measure the heat of transport, Q* , of hydrogen and of deuterium dissolved in a iron and in nickel, and of hydrogen in Feo.6Nio.4 in the tempevature range 400° to 600°C. For all these systems, Q* is negative and has a large temperature coefficient; an isotope effect can be established for the solutes only in nickel. The magnitude of Q* is considerably larger than the activation energy, E , for migration in the case of these isotopes in a iron, so that all variants of the Wirtz model must be rejected. The phenomenological definition of Q* is developed to show that Q* is related to the mechanisms by which the activation energy is dissipated back into the lattice, and that Q*/E is a function of the ratios of the mean free paths of electrons and of phonons to the distance of jump of the diffusing atom. A correlation is shown to exist between the sign of Q* in thermal diffusion and that of the effective charge in electro migration, and may be understood as due to the large ratio of the mean free path of electrons to that of phonons. THE study of nonisothermal diffusion in the solid state is of interest because certain aspects of the mechanism of diffusion are made manifest which remain concealed though still present in the isothermal case. The thermodynamics of irreversible processes characterizes nonisothermal diffusion, known as thermal diffusion or as the Ludwig-Soret effect, by a quantity, Q*, called the heat of transport, which essentially measures the sign and the magnitude of the steady-state concentration gradient produced by the imposed temperature gradient. The problem then is to understand the quantity Q* at the atomistic level. There does not exist a theory for the atomistic interpretation of the heat of transport. There are, however, two classes of simple models which seem to afford some physical insight into Q*. Wirtz's model1, z and its subsequent generalizations partition the activation energy, E, for the migration of the atom spatially about the region of the migrating atom, so that Q* is the difference between the portion of the activation energy centered about the original site of the jumping atom and that portion about the arrival site. Clearly, the magnitude of Q* cannot on this model be larger than the activation energy for migration. The model of Oriani3 also considers the spatial distribution of E not only before but also after the atomic jump, and Q* is related to the variation of the spatial distribution of E that is produced by the jump. The simplest kind of system with which to compare the consequences of these ideas is the interstitial solid solution, since one may easily choose a temperature at which only the interstitial component moves, the solvent lattice serving as a completely satisfactory frame of reference. Thus, one avoids complications arising when both species in a binary system move. In addition, one avoids the necessity of knowing the energy for the formation of a vacancy, something which is needed for the analysis of thermal-diffusion data on metals which diffuse by the vacancy-exchange mechanism. However, the number of well-measured interstitial systems is extremely small, and, in particular, there are almost no data in the published literature for the temperature dependence of the heat of transport. If one works with solutes which are gases in the pure state at ordinary temperatures, one may use the technique of thermo-osmosis4 which permits thermal diffusion to be measured over a small temperature difference so that the temperature dependence of Q* can be more easily determined. The choice of dissolved hydrogen in iron and nickel was based on these considerations as well as on the desire to look for an isotope effect associated with localized

Jan 1, 1965

By Karen Mikkola, Gerald Luttrell, Jaisen Kohmuench, Glen Oswald, Michael Mankosa, Tracy Westerfield

Hydraulic separators are commonly used for particle size classification and gravity concentration of minerals and coal. Unfortunately, the efficiency of these processes can be quite low due to poor equipment design and variations in feed consistency. To help alleviate these problems, an industry-driven R&D program has been undertaken to develop a new generation of hydraulic separators that are more efficient and less costly to operate and maintain. Two of the most promising technologies, the CrossFlow and HydroFloat separators, have now been tested at industrial sites. The data obtained from these sites have been used to illustrate the potential performance improvements that can be realized through the application of these high-efficiency separators.

Jan 1, 2005

By M Lewis, A Cook

This paper is based on the technology and functionality of a Modular Mining IntelliMINE« system which is a real-time decision-making tool. The IntelliMINE« system, incorporating Dispatch, is a fully Integrated Mine Management System. Measuring, quantifying and analysing the performance of mining is considered a fundamental and strategic step towards changing the nature of technical and operational decision-making at the majority of international mining corporations. Successful implementation of electronic data capture devices and computerised tools have enabled many mining operations to improve their competitive position with an improvement in the utilisation of the key assets, mineral resources, capital mining equipment and human resources. Real Time Mine Management Systems are designed to direct the emphasis away from collecting data and focus decision makers on the real issues with well-presented and reliable information. The systems provide a common stream of information to enable senior management, operations, maintenance, technical and process plant staff to make complementary decisions based on reliable, accurate and timely data. The mine asset information tools focus all employees on performance and give them feedback on their area of responsibility. The resulting tangible benefits can be delivered in different forms depending on the mining method, ore type, workplace culture and the current competitive position. Typical areas of improvement reported by system users are:reduction in capital expenditure on mining equipment fleets; more effective planning and budgeting parameters and procedures; increased control over ore-extraction and processing; increased employee accountability and organisational performance; and improved co-ordination between planning, operations, maintenance and processing. These improvements can be delivered in different forms depending on the status of the mine and commodity markets. In times of market oversupply and low commodity prices, the benefits can be delivered to the bottom line in terms of reduced cash costs, reduced capital and operating resources to maintain constant production. In times of market expansion, existing capital resources will be more productive delivering increased production and revenue. Mine management systems have the potential to transform a traditional mine operation into a learning organisation with an improved understanding of the critical performance issues and enable development of relevant strategies to continually identify and eliminate operational inefficiencies. The effectiveness of each strategy and operational change can be accurately monitored and its success (or otherwise) will be quantified. The latest downturn in the world metal prices has forced many mining companies to focus on cost reduction and productivity improvements as a means of remaining competitive. Maintenance represents a significant proportion of the overall operating costs in the mining industry. A structured proactive maintenance approach such as Reliability Centered Maintenance (RCM) can achieve significant cost reductions and productivity improvements. Remote condition monitoring systems are becoming increasingly commonplace and have the potential to identify problems prior to failure. Detection of equipment degradation prior to failure will enable repairs to be scheduled, thereby reducing costs and interruptions to production.

Jan 1, 2000

Determining the controls of high-grade mineralisation at Vera Nancy requires careful data collection and assessment on a global and specific deposit basis. The techniques developed over 60 years ago to analyse structure, grade and width data are just as applicable today and can be enhanced using modern geological modelling software. High ore grades at Vera Nancy are controlled by both the primary geometry of the mineralised structure and the intersections of the main mineralised veins with subordinate splay veins. The main mineralised structure dilated as a consequence of extensional tectonics while the splays acted as conduits bringing oxidising surficial fluids into mixing zones precipitating high gold grades. Near-mine exploration is focussed on identifying zones of vein flexure and splay interaction to locate the relatively small high-grade shoots. Data modelling in a 3D environment is an essential process for understanding the geometry of the system being explored.

Jan 1, 2000

By J. N. Sicking, F. H. Brinkman

A new method for obtaining equilibrium vaporization ratios (K-values) for reservoir fluids has been developed and tested. By application of the method, complex experimental measurements of liquid and vapor phase compositions are eliminated. This simplified technique reduces the cost of experimental equilibrium-ratio data for reservoir studies of condensates and volatile crude-oil systems. The method is designed for systems of constant composition and, therefore, is best suited for depletion studies where compositional changes at high pressures are minor. The basic data required, in addition to the composition of the initial reservoir fluid, are the relative vapor-liquid volumes and densities at reservoir temperature and variom reservoir pressures. Tests demonstrated that the method predicts equilibrium ratios accurately for condensates. A single test on a crude oil was not conclusive; further testing will be necessary before the accuracy of the method can be determined for crude-oil systems. In addition to determining equilibrium ratios, the calculation method provides information on the physical properties of the "plus" component in the vapor and liquid phases. The "plus" component is that mixture of components heavier than the least volatile fraction analyzed. This information is useful in studies of both natural depletion and cycling operations for condensate reservoirs where the heptanes-plus component in the gas phase is produced from the reservoir. INTRODUCTION As more volatile oil and condensate reservoirs are found, the use of phase behavior techniques to predict their performance is increasing in importance. These techniques have long been used for condensate fields and have more recently been applied to crude-oil fields containing oils of medium-to-high volatility. In these phase behavior methods, equilibrium ratios (K-values) are used to predict compositional changes in the reservoir fluids—thereby accounting for the recoverable oil that exists in the gas phase. The reliability of the predictions depends to a large extent on the equilibrium ratios used. These values must be obtained for each component for the entire pressure range being investigated. Unfortunately, because of the complex nature of hydrocarbon mixtures, accurate K-values are hard to obtain. The equilibrium ratios for a particular component will vary not only with the temperature and pressure, but also with over-all composition of the system. The importance of composition is quite critical at elevated pressures, but becomes negligible at pressures below about 300 psia. Therefore, because most phase behavior problems involve the high-pressure region, each fluid system becomes a special case. Experimental programs to determine characteristic K-values are quite difficult and time-consuming. Thus, it is often necessary to resort to approximations of the K-value data. Charts giving K-values for various mixtures and classes of mixtures are available in the literature. However, there are two major difficulties in using them: (1) the K-values of the "plus" component (that mixture of components heavier than the last one analyzed) must be obtained by extrapolation from the K-values of the other components; and (2) the K-values obtained must finally be adjusted by trial and error to agree with observed volumetric data. To eliminate these difficulties, a new method of determining equilibrium ratios was developed. Briefly, after the composition of the system as a whole has been analyzed, the method uses empirical correlations and the gross fluid properties of the system (relative vapor-liquid volumes and densities) to calculate K-values. Because the calculative procedure is long, it is best solved on a digital computer. About one hour of machine time on an IBM 650 computer is required to develop a K-chart for the fluid being examined. DEVELOPMENT OF THE METHOD OF OBTAINING K-VALUES Equilibrium ratios are defined as the ratio of the mole fraction of a component in the vapor phase to its mole fraction in the liquid phase. This statement is expressed in Eq. 1. A typical plot of equilibrium ratios for a particular system is shown in Fig. 1. It should be noted that, at pressures near the saturation pressure, the K-values appear to converge to a common point. This apparent convergence point is called the convergence pressure and is a characteristic of the system involved. Various empirical correlations of K-values have been noted. It has been observed that an isothermal plot of

By P. C. Pistorius, M. P. Maphutha, J. D. Steenkamp

Advanced high-strength steels (AHSS) are sophisticated materials being developed by the steel industry to mitigate challenges related to the performance of motor vehicles. To meet the requirements of AHSS, the ferromanganese alloys (FeMn) utilized in the production of the steel are required to contain acceptable levels of unwanted impurities, i.e. P, S, N, H, and C. The focus of the current study was to investigate dephosphorization of ferromanganese to produce a low-P alloy that could be effectively utilized in the production of AHSS. The study involved conducting laboratory-scale testwork to study the efficiency of CaO-based slag systems to dephosphorize FeMn alloys. The addition of Na2O, CaF2, and BaO to MnO-CaO-SiO2 slag was considered. The test work was carried out in a 25 kW induction furnace at temperatures of 1350°C, 1400°C, and 1450°C. The P partition coefficient (Lp) remained small at <1, which is an indication that dephosphorization had not been achieved. The baseline slag, comprising 40%CaO-40%SiO2-20%MnO, reported higher Lp values. Addition of Na2O and CaF2 did not show any further benefit. Substituting half of the CaO by BaO, resulted in similar Lp values to those of the baseline slag under conditions of 1350°C and 1450°C at 30 minutes. In summary, based on the Lp values obtained, the conditions investigated with the CaO-based slags appeared to have been unfavourable for dephosphorization of FeMn alloys, as most of this impurity element remained in the alloy.

Sep 1, 2021

By R. Burrell, N .. L. Lapp

"Except for asthma and pulmonary infections, the types of lung disease that have been of immunologic interest the longest are the various mineral pneumoconioses. Because of their chronicity, type of pathology produced, and well-known immunotoxic properties associated with the dusts inciting them, the pneumoconioses have long drawn attention to the possibility that the immune system has not only been modulated but that its effectors have possibly contributed to their pathogenesis. All of the mineral dusts reviewed here have definite immunomodulating properties and act on various cellular and molecular components of the immune system. Further, each has an immunotoxic potential to induce either hypersensitivity (as in the case of beryllium) or other types of immune injury. This article reviews the immunologic aspects of the four major occupational minerals that have an immunologic impact on the lung: asbestos (particularly chrysotile), silica or quartz, beryllium, and coal mine dust.These agents have many things in common, yet each is distinctive. Although the possibility still exists that these mineral particles can adsorb intrinsic tissue antigens or extrinsic organic antigens to their surfaces and initiate immune responses to the adsorbed antigens, only one, beryllium, can act as an antigen itself. Silica is a profound macrophage toxin and thereby exerts many effects on those factors controlled by macrophages. Asbestos has undergone the most immunologic studies resulting in a much dearer picture of how it may contribute to immunopathology. Coal mine dust is the agent about which least is known immunologically, partly because there is no such thing as purified coal mine dust or a standard by which coal mine dust can be defined. Indeed, there are studies that use only the dust from the ground coal itself, whereas other studies use the total dust collected from air samples of a working mine in the belief that other types of dusts (e.g., silica from roof bolt drilling, from sand ground on the rails by cars, and from surface drilling) contribute to the disease (Figs. 1 to 5). This properly is coal mine dust and is poorly characterized. Yet, workers exposed to these dusts share similar reactive characteristics and they may be considered collectively as well as individually."

Mar 1, 1992