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By Peter A. Adcock, Rob Fraser

Interest in monitoring nucleation overpotential in electrometallurgical processes dates back some 40 years or more. Conversely, remarkable progress has been made in recent years on describing in detail the processes involved in the formation of thin films by electrodeposition. The newer body of work underscores a need for greater clarity in speaking about the role of nucleation and in the acquisition and interpretation of nucleation overpotential measurements – the aim of this paper. In electrometallurgy, it is generally desirable to form deposits that remain smooth, compact, and relatively fine-grained while the deposit grows to a thickness on the order of 5-10 mm, about 100 times thicker than technological thin films. Hence, we distinguish two kinds of nucleation that can result in formation of new grains:- (1) initial nucleation (onto the substrate surface) of islands that coalesce into growing deposit, and (2) ongoing nucleation of new grains on the deposit surface long after the substrate has been covered and ceases to have a direct influence. Nucleation overpotential of the first type should be measured on an electrode surface truly representative of a real industrial substrate. The second type requires judicious choice of electrode material – an “ideal foreign substrate”. In general neither the industrial substrate nor native metal to be deposited is suitable for measurement of the second type of nucleation overpotential, because of interference by other processes. For the future, clear terminology is needed to distinguish these two types of nucleation potential. The second is the one for which the type of plot dubbed by Moats and Derrick as an “Adcock plot” and by us as a “Kerby-Adcock plot” was first conceived and correlated with relatively thick zinc electrodeposits. The data of Moats and Derrick showing trends for copper electrodeposition on stainless steel and on copper electrodes are interpreted within this framework.

Jan 1, 2016

By S. H. Ash

THIS REPORT covers the second in a series of five projects into which the Conowingo tunnel system has been divided for geographical and practical reasons. It outlines the construction work contemplated-to sink two shafts on the line of the main tunnel that are designated the Nos. 9A and 11 shafts, to turn off from the No. 9A shaft the Lansford and Lykens laterals, and to drive portions of the main tunnel. An emergency pumping plant, consisting of 2 separate pumprooms, each containing 3 horizontal-type centrifugal pumps of 100,000-gallons-per-minute (g. p. m.) capacity, will be constructed at the No. 9A shaft. From the No. 11 shaft will be turned off the Trevorton lateral and portions of the main tunnel, which will connect with the section driven from the No. 9A shaft. Under the proposed project, the Lansford lateral will be driven for a distance of 2 miles, the Lykens lateral for a distance of 10.56 miles, and the Trevorton lateral for a distance of 20 miles. To drive the Lykens and Trevorton laterals for the distance indicated, several construction shafts and slopes must be sunk to permit efficient and safe construction.

Jan 1, 1955

By Stephen A. Swan

Certain types of mobile surface mining equipment are required to be equipped with rollover protective structures (ROPS) capable of protecting the operator in case of a rollover accident. The Bureau of Mines has developed ROPS performance criteria for wheeled front-end loaders. This report reviews the development of rollover test procedures and subsequent testing of ROPS for 52,000-, 286,000-, and 390,000-lb gross vehicle weight (GVW) loaders. The program consisted of both dynamic (roll) and static tests to assist in the development of the ROPS performance criteria. Each test included extensive instrumentation and photographic documentation to fully evaluate the performance of the ROPS. Data summarizing side, longitudinal, and vertical force and deflections are included. The data indicate that for loaders in excess of 240,000 lb, GVW, a side force-to-mass ratio of 1.0 and an energy-to-mass ratio of 6.0 appear to be adequate criteria to protect an operator in the event of a 5400 rollover. For smaller machines, Society of Automotive Engineers (SAE) 11040 performance criteria provide adequate protection. Longitudinal loading, though not ad-dressed in previous ROPS performance criteria, was shown to be a potentially significant factor in ROPS failure. Longitudinal loading and energy criteria equal to 80 pct of side loading criteria are recommended.

Jan 1, 1988

By W. D. Striffler

Land disturbed by surface mining in Colorado and other western states has increased substantially over the past several years and is likely to increase even more in the future. This study was initiated to provide basic information on hydrologic and erosional characteristics of regraded coal spoils in Colorado as an aid for planning future reclamation activities. Eleven of twenty-one surface mines licensed in Colorado were sampled during the summer of 1980 and 1981. Mines not sampled included mines which had not progressed to the point that reclamation had begun, and mines where operators denied permission to sample. All coal regions were sampled with the exception of the San Juan Coal Field. Physical and hydrologic characteristics of regraded coal spoils in Colorado were determined using standard field and laboratory procedures. Field sampling included characterization of sites (slope, vegetation density, proportion of surface rock, bare soil, etc.) and infiltration measurements using a l-meter square drop former raining on a 1/2 square meter rectangular plot frame. Core samples collected in the field were analyzed for saturated hydraulic conductivity, bulk density, organic matter, moisture retention and texture. The erosion potential of each site was determined using the Universal Soil Loss Equation (USLE). Results of the sampling indicate that infiltration rates vary widely both within and between sites. However, definite trends with respect to coal fields are apparent. For example, the Green River (Yampa) coal region had a wide range of sampled infiltration rates (1.2 to 5.1 cm/hr). However, most of the sites clustered towards the low end of the range. The North Park (Marr Strip) also was rated at the low end of the infiltration range (2.0 to 3.0 cm/hr). Average infiltration rates for the Canon City and Uinta Coal Regions were at the high end of the range (4.9 to 5.5 cm/hr). Multiple correlation analysis of infiltration rates vs. site characteristics showed that infiltration rates were most closely correlated with the depth of wetting, the amount of mulch cover, and site slope. The depth of wetting was highly correlated with the depth of the topsoil and the bulk density of the spoil. In general, the topsoil at all sites appeared to be highly permeable to water intake but once saturated, subsequent infiltration depended upon characteristics of the underlying spoil. Vegetation cover affected infiltration on individual mine sites but was not as pronounced as topsoil characteristics or mulch. Erodibility of topsoil and spoils, as determined by Wischmeier's "K" factor, ranged from 1.34 to 0.56 tonnes/ha. (topsoil) and 1.25 to 0.66 tonnes/ha. (spoils). Definite trends in erodibility are evident. The Green River (Yampa) Coal Region displayed consistently higher erodibilities (1.34 to 0.75 tonnes/ha.) than other coal fields (0.72 to 0.56 tonnes/ha). Lowest erodibilities were observed in the Uinta, North Park, and Raton Mesa Coal Regions (0.56 to 0.62 tonnes/ha). Erodibilities of underlying spoils showed similar trends as the topsoils. Erosion potential (the product of soil erodibility and rainfall erosivity) was detennined using calculated ?K? factors and rainfall erosivities (R) taken from Clyde (1976). Results show that the Delagua coal field, Raton Mesa Coal Region had the greatest erosion potential due to the high rainfall energies in the region, while the North Park and Uinta Coal Regions had the lowest potential erosion.

Jan 1, 1981

By T. A. Henrie

One objective of Project Gnome is to study the feasibility of a phase of the Plowshare program recovering thermal energy from an underground nuclear explosion. The test will be conducted in an underground salt deposit. It is anticipated that some of the energy thus released will be stored as thermal energy in molten salt. This report describes the pre-Gnome experiments conducted at the Federal Bureau of Mines Metallurgy Research Laboratory, Boulder City, Nev. The objectives of this study were to determine the problems involved in the recovery of thermal energy from molten salts to assist in planning the experimental program for the Gnome project.

Jan 1, 1961

Electrochemical behaviors of synthetic and natural enargite in buffer solutions have been investigated using open circuit potential, stationary polarization and cyclic voltammetry as functions of solution pH, scan direction, scan range, scan rate and dissolved O2. The results indicate that the electrochemical behaviors of synthetic and natural enargite are very similar; solution pH, scan direction, scan range and scan rate have remarkable effects on the electrochemical behavior of enargite while dissolved O2 has little effect on the electrochemical behavior of enargite. The potential range in which enargite possesses the ability of passivation is from ?0.9 V to + 0.83 V vs. SCE. Enargite is most stable in neutral and alkaline solution around potential ?0.2 V vs. SCE. The main oxidation products on enargite surface in alkaline solution are Cu(OH)2 while the potential imposed on it is within the range of ?0.2 V to 0.33 V vs. SCE and Cu(OH)2 + S0while the potential applied is higher than 0.52 V vs. SCE.

Jan 1, 2014

By P Dowd, R Jeuken, C Xu

In Australian coalmines there are a number of coal quality parameters that are measured by analysing samples from boreholes. The data points are used to generate spatial models of these parameters, typically using inverse distance as an interpolation method. Numerous additional boreholes are drilled which have geophysical logs measured downhole but from which no coal quality samples are taken. Full suites of coal quality analyses are expensive and time consuming to drill and sample. If geophysical proxies for coal quality could be used, this would greatly improve the accuracy of the resource estimation without additional cost.This paper examines two of the most important coal quality parameters – ash and volatile matter – and assesses the results of a number of geostatistical interpolation methods. The aim is to improve the accuracy of the interpolated models. Auxiliary variables from geophysical logs are also trialled to improve the estimation.A multivariate analysis of ash, volatile matter and several auxiliary variables of a selected coal seam was undertaken in a spatial context, using variography. This was used to construct a model of co-regionalisation that relates all of the variables as manifestations of an underlying geological theme.The traditional inverse distance interpolation approach was compared to ordinary kriging, universal kriging, co-kriging, regression kriging and kriging with external drift approaches. The relative merits of the six interpolation methods were compared by removing all points, one at a time and estimating at the thus known location. The mean error and the root mean square error were evaluated as a measure of bias and precision.This paper demonstrates that there is significant opportunity to improve the estimations of coal quality when using kriging with external drift. For example, the results show that when using the depth of a sample as an external drift variable there is a significant improvement in the accuracy of estimation for volatile matter. Furthermore, when using borehole wireline density logs as an auxiliary variable for ash content, there is improvement in the estimation of the in situ ash. The underpinning reasons for this are discussed in the context of the underlying geology and the physical properties of the coal. These findings hold promise for utilising cheaper proxies for coal quality parameters to dramatically improve data density and the quality of estimations.CITATION:Jeuken, R, Xu, C and Dowd, P, 2017. Improving coal quality estimations using geostatistics and auxiliary variables, in Proceedings Tenth International Mining Geology Conference 2017, pp 157–168 (The Australasian Institute of Mining and Metallurgy: Melbourne).

Sep 20, 2017

By W. A. Haley

This is the second of a series of publications that describes the progress of mechanical longwall coal mining in the United States in which a German coal planer was employed.3/ Details of the equipment, a description of its operation, and the results obtained in mining the experimental panel were published in the preceding report. Experimental mining with the planer in the first panel showed an improvement in performance over conventional mining methods at the coal company's Stotesbury 11 mine. The work, which was begun on an experimental basis, soon proved successful, and the coal company purchased the equipment for continued use. Two panels, adjacent to the first, were developed and mined with the planer. Each of these panels was shorter than the preceding one because water seepage from a surface creek limited development. On completion of mining in the third panel, the planer equipment was moved by the cooperating company to a nearby mine operated in the same coal bed where a large area of coal suitable for planer mining is available.

Jan 1, 1954

By W. A. Parks

Stone that may be applied to purposes of construction is available in nearly all the inhabited parts of Canada, the most important exception being the prairie region, but, even here, the deficiency is overcome in many parts by a wealth of glacial field-stones. In many parts of the country, also, the accessible stone is of a quality so poor that brick is more generally used. There is a great difference, however, between stone that 'may be used' and stone suitable for buildings of a monumental type or even for 'trimmings' on the better class of dwelling in the cities and towns. It is in the latter sense that the expression 'building stone' is commonly used. Thus restricted the term includes varieties of sandstone, limestone, and granite, using the latter word in the custom of the quarryman, not only for the true granite of the geologist but for many other igneous rocks as well. Building stone of high quality grades imperceptibly into stone suitable for monuments, particularly in the case of the granites. The present review will deal with building and monumental stone in this restricted sense and will omit marble, although that material has been used to some extent for building. For instance, the Great West block in Winnipeg is built of marble from British Columbia.

Jan 1, 1925

By P. Bissert, M. Klein, L. Yan, D. Yantek, R. Matetic

"U.S. Mine Safety and Health Administration (MSHA) regulations require underground coal mines to use refuge alternatives (RAs) to provide a breathable air environment for 96 hours. One of the main concerns with the use of mobile RAs is heat and humidity buildup inside the RA. The accumulation of heat and humidity can result in miners suffering heat stress or even death. MSHA regulations require that the apparent temperature in an occupied RA not exceed 95 °F. To investigate this, the U.S. National Institute for Occupational Safety and Health (NIOSH) conducted testing on a 23-person tent-type RA in its Experimental Mine in a test area that was isolated from the mine ventilation system. The test results showed that the average measured air temperature within the RA increased by 9.4 °C (17 °F) and the relative humidity approached 94 percent at the end of a 96-hour test. The test results were used to benchmark a thermal simulation model of the tested RA. The validated thermal simulation model predicted the volume-weighted average air temperature inside the RA tent at the end of 96 hours to within 0.06 °C (0.1 °F) of the average measured air temperature. IntroductionIf an accident occurs in an underground coal mine, miners who fail to escape from the mine can enter a refuge alternative (RA) for protection from adverse conditions, such as high carbon monoxide levels. One of the main concerns with the use of mobile RAs is the potentially adverse thermal environment inside an RA from the metabolic heat of the occupants and the heat released by the carbon dioxide (CO2) scrubbing system. Moreover, the humidity within the RA will increase through occupants’ respiration and perspiration, and from the chemical reaction within the CO2 scrubbing system. The accumulation of heat and humidity can result in miners suffering heat stress, heat stroke or even death."

Sep 1, 2016

By Hardwick F. W., O'Shea L. T.

The survey covers: coal-mine lighting prior to the invention of the safety-lamp, including candles, the flint-and-steel Spedding mill, and mirrors; the growth in knowledge of firedamp; the Society in Sunderland for Preventing Accidents in Coal Mines; Dr. Clanny's blast lamps and steam lamps; George Stephenson's tube-and-slider lamp, triple-tube lamp, punched-plate lamp and gauze Stephenson lamp; Sir Humphrey Davy's lamps; the controversy over invention priority, and other early forms of safety-lamp; 1816-1835 developments including the lamps of Upton and Roberts, M.Mueseler, John Martin, Dr. Clanny (new 4th lamp), M. Agre, John Newman, Gossart and Roberts, Francis Ellis, John Dillon and Mr. Wood (refrigerating lamp); 1836-1843 developments, notably of Mueseler lamps; 1844-1866, including lamps of the Davy, Clanny, Boty, Eloin and other types; 1867-1879, including the Gray lamp; 1880-1887, including the Marsaut lamp; and 1888-1913. Detailed reference is made to the findings of various relevant Royal Commissions and appendices include a list of the safety-lamps described in an appendix to the 1886 report and a publications list. The paper was prepared for the International congress of mining, metallurgy, applied mechanics and economic geology to have been held in London in July 1915. Discussion (p.718-724) includes a brief comment by Blackett W.C. and a longer contribution by Ashworth J., with the authors' response

Dec 1, 1916

By Willis Beckering

The Bureau of Mines designed a cell having four variable compartments in series to facilitate analysis of multicomponent mixtures. Use of the cell considerably decreases the time required for differential absorption analyses. A solution of a major component is placed in each compartment, and the light absorbed by each of these components is varied by increasing or decreasing the path length of the appropriate cell. Simple calculations then establish the amount of the component present. In analyzing unknown mixtures, compensation is made for compounds known to be present, and the differential spectrum representing components not accounted for is recorded and analyzed.

Jan 1, 1966

By G. G. Hatch

FOLLOWING World War II there was an urgent need for the development of domestic sources of ilmenite to take care of the expanding needs of the titanium dioxide pigment industry. In addition, there was the interest by the pigment manufucturers and others in titanium metal. Prior to the war the pigment industry in the United States had obtained its major tonnage of ilmenite, analyzing 55- ?60 per cent Ti02, from India. However, as a result of the shipping situation which developed during the war, the pigment manufacturers had to consider the use of lower grades of ilmenite located on this continent .and several companies undertook extensive exploration programmes to locate and develop such orebodies. Probably the most significant deposit that was found as a result of these ?programmes was the orebody .at Allard Lake, Quebec, owned by the Quebec Iron and Titanium Corporation. This ?Company was formed in 1948 by the Kennecott Copper Corporation and the New Jersey Zinc Company to mine this ilmenite ore and treat it in electric furnaces to produce titanium dioxide slag for the pigment industry and iron for the steel industry.

Jan 1, 1956

By C. D. King

The key to maximum production of ingots for the war effort is maximum production of pig iron. For any given furnace and ore, the most important single influence on blast-furnace production is the quality of the furnace coke. It is generally recognized that undoubtedly deterioration of Pittsburgh coking coals will be accelerated by the depletion of some of the better grades of coal; the extension of mine mechanization, with attendant degradation of coal quality; and the opening of new coal fields, some of which are known to be fairly high in sulphur. All of these factors, contributing as they do to higher ash and sulphur, and not infrequently to inferior quality of coke, made it desirable that an extensive study be undertaken to determine the effect of washing some coals that closely approximate the average chemical composition of coking coals to be expected in the future by the subsidiaries of the United States Steel Corporation in the Pittsburgh district. It was deemed advisable to study the improvement obtained by washing such coals and to determine the need for supplementing the existing coal washery at Clairton to assure continued maximum production of pig iron from presently available furnace stacks. The existence of the coal washer at Clairton made it possible to conduct tests on coals used in raw form and on similar coals after washing. This study covers an investigation of the quality of furnace coke as affected by washing coking coals, and is confined to the use of 100 per cent high-volatile Pittsburgh seam coals from Fayette and Greene Counties in the manufacture of furnace coke. It covers the improvement in chemical and physical properties as well as the degree of uniformity in coke obtained by washing these coals, and includes the effect on blast-furnace production and practice. The test period involved is four months; the plants, Clairton by-product coke plant, and the Carrie No. 1 and No. 2 blast furnaces at Rankin, Pa., Carnegie-Illinois Steel Corporation. Clairton By-product Coke Plant and Coal Washer The Clairton by-product coke plant carbonizes 30,800 net tons of coal daily in 22 batteries containing 1482 ovens. Three oven sizes are used, commonly known as wide, medium, and narrow types, recognizing the difference in oven width, These ovens also differ in height and length. The present coal washer has a daily capacity of approximately 14,000 tons, leaving 16,800 tans to be carbonized in raw form. Washed coal is used on all the narrow ovens and on three of the six batteries with ovens of medium width, raw coals being used on all the remaining ovens. The customary arrangement is

Jan 1, 1944

By C. D. King

The key to maximum production of ingots for the war effort is maximum production of pig iron. For any given furnace and ore, the most important single influence on blast-furnace production is the quality of the furnace coke. It is generally recognized that undoubtedly deterioration of Pittsburgh coking coals will be accelerated by the depletion of some of the better grades of coal; the extension of mine mechanization, with attendant degradation of coal quality; and the opening of new coal fields, some of which are known to be fairly high in sulphur. All of these factors, contributing as they do to higher ash and sulphur, and not infrequently to inferior quality of coke, made it desirable that an extensive study be undertaken to determine the effect of washing some coals that closely approximate the average chemical composition of coking coals to be expected in the future by the subsidiaries of the United States Steel Corporation in the Pittsburgh district. It was deemed advisable to study the improvement obtained by washing such coals and to determine the need for supplementing the existing coal washery at Clairton to assure continued maximum production of pig iron from presently available furnace stacks. The existence of the coal washer at Clairton made it possible to conduct tests on coals used in raw form and on similar coals after washing. This study covers an investigation of the quality of furnace coke as affected by washing coking coals, and is confined to the use of 100 per cent high-volatile Pittsburgh seam coals from Fayette and Greene Counties in the manufacture of furnace coke. It covers the improvement in chemical and physical properties as well as the degree of uniformity in coke obtained by washing these coals, and includes the effect on blast-furnace production and practice. The test period involved is four months; the plants, Clairton by-product coke plant, and the Carrie No. 1 and No. 2 blast furnaces at Rankin, Pa., Carnegie-Illinois Steel Corporation. Clairton By-product Coke Plant and Coal Washer The Clairton by-product coke plant carbonizes 30,800 net tons of coal daily in 22 batteries containing 1482 ovens. Three oven sizes are used, commonly known as wide, medium, and narrow types, recognizing the difference in oven width, These ovens also differ in height and length. The present coal washer has a daily capacity of approximately 14,000 tons, leaving 16,800 tans to be carbonized in raw form. Washed coal is used on all the narrow ovens and on three of the six batteries with ovens of medium width, raw coals being used on all the remaining ovens. The customary arrangement is

Jan 1, 1944

By G. J. Grott

Direct Production Costs for Solar Sa 1t approximate the trucking cost for 160 Km. Operations near markets appear unusually attractive at first look. However, many desert operations have been plagued by dust storms yielding salt too high in insolubles for most uses. This paper relates the history of a successful operation in a dust storm area. Saturated brine from the solution mining of LPG storage caverns is evaporated in solar ponds yielding 99.95% sodium chloride (dry basis). Purchased energy is one-eighth that of vacuum pan operations. Production scale tests have proved it works at another desert location using a more complex brine. A new approach for refining soluble salts at ambient temperatures is demonstrated by bench scale and pilot work. Again, savings in purchased energy exceed 80%, even when temperatures are raised to reduce refining time.

Jan 1, 1988

By Pekka Hanniala

The Outokumpu Flash Smelting process today is the most feasible method for copper matte smelting. The economic feasibility of the process has always been one of the main decision making criteria in smelter projects. Thus, today about 50 % of the world primary copper production utilizes Outokumpu Flash Smelting Technology. However, in the future, environmental criteria will have stronger and stronger impact on decision making. Flash Smelting technology offers the best pollution control features of any process. today. It is foreseen that, in the near future, the global trend will be that all the smelters must decrease their emissions at an accelerating rate, compelling the smelters to make increasingly larger investments on environmental protection. In most of smelters ?today, Peirce-Smith converting and transfer of the molten material in ladles are the number one pollution source. The key today for copper converting and minimizing emissions is the Kennecott-Outokumpu Flash Converting process, which has proven to be the most effective converting method in terms of pollution control and, production efficiency including capital and operational costs. Outokumpu Flash Smelting technology is applicable also for small to medium scale smelters but the most interesting area is the upper capacity limit for smelting in one line, which has not yet been reached. We predict that by the year 2000 to 2005, there will be at least one smelter which produces 500,000 tonnes of Cu per year based on one Flash Smelting and Flash. Converting unit. The current state-of-the-art of the Outokumpu Flash Smelting - Flash Converting process is presented in this paper as well as some new options for copper production to be utilized in the near future but which are available already today.

Jan 1, 1998

By Chang Wei, Zhigan Deng, Jiqiang Liao, Minting Li, Hongsheng Xu, Yan Song, Cunxiong Li, Xingbin Li

"Abstract: Direct ?otation of oxidized zinc-lead ore is characterized by recovery of zinc and lead only around 55% and 50%, respectively. Mineralogical analysis shows that the sample used in the present study is a carbonate hosted zinc-lead ore, with a zinc and lead carbonate content that accounts for 80.14% and 75.63% of the total minerals, respectively. The carbonate hosted zinc-lead ore was hydrothermally sulfidized with elemental sufur and the experimental data indicated that under the conditions employed up to 75% zinc and 82% lead sulfidation extent were achieved. As a result of pre-sulfidation followed by flotation, the recoveries of zinc and lead into flotation concentrate were over 90%. A flotation concentrate was obtained with 52% Zn and 37% Pb from the materials which was treated by sulfidation.IntroductionSulfide ores are the primary source of zinc and lead, and they are becoming depleted; thus, metallurgical investigators are interested in using abundant oxidized zinc-lead ore reserves. The high-grade zinc-lead oxidized ore, which normally has a zinc content higher than 15%, can be disposed of by acid leaching and electrolysis. However, the low-grade ore, which has a zinc content lower than 10%, is difficult to smelt with pyrometallurgy and hydrometallurgy, and the processes are very complicated and expensive in terms of production flow and energy consumption. Therefore, making the low-grade oxidized zinc-lead ore more beneficial has become more important in recent years. Flotation is the most common process, and the primary method of recovering zinc and lead from sulfide or oxide minerals. It is well known that there is a difference between sulfurized and oxidized minerals regarding their separation by flotation. Flotation of zinc and lead oxidized minerals is extremely complex because of the similarities in the physicochemical and surface chemistry of the constituent minerals. There are no known direct-acting collectors capable of producing single metal concentrates [1-3]."

Jan 1, 2012

By G. F. Loughlin

Nearly 55 years have elapsed since the U. S. Geological Survey was organized. During this period the mineral industries have grown from infancy or early childhood to well developed maturity, and some mining industries appear to be declining. Decline in mining is even more conspicuous in certain districts, or even states, than in any mining industry as a whole, and discoveries or developments of important new districts have been very few in recent years. Our reserves of most metals and nonmetals are adequate for many years of normal production, subject to changes in rate of exploitation that may be caused by foreign competition and by changes in technology and market conditions; but the declining production of many districts and the scarcity of important new discoveries to compensate for them is cause for some apprehension. It is likely that future production will depend to a considerable extent on deep exploration and on the thorough examination of places in and adjoining existing districts where significant outcrops are lacking and only apparently insignificant geologic features offer encouraging clues—more so than on the discovery of entirely new districts. Even the possible discovery of new districts, which have escaped the intensive search by the nontechnical prospector, must be dependent on geologic information. There is therefore no need for argument as to the value of geology to the mining industry; and the need of continuing to advance the science. The U. S. Geological Survey's past contributions to mining geology, as expressed in its official reports and other publications, are recognized by Ransome in his historical review of mining geology in the Lindgren volume.' These contributions have helped to form the basis of modern mining geology, which has grown rapidly in the last 25 years. This growth has witnessed the organization and maintenance of geologic staffs by mining companies in several districts, and their detailed work, together with the fact that nearly all of the larger mining districts have

Jan 1, 1935

By Eugene V. Cilento, R. Clark Lantz, K. A. DiGregorio

"This laboratory bas developed a sensitive electro-optical method to quantify the initial rate (R) and total amount (MAX) of superoxide (02) produced by single pulmonary alveolar macrophages (PAM). The method uses a microscope-based TV system to visualize PAM in culture, and to video record the images during the time the cells produce 02. MAX and R are calculated from measurement of temporal changes in optical density in the images due to precipitated diformazan formed by the reaction of O2-, produced by each PAM, with nitroblue tetrazolium present in the culture medium. To date, values of Rand MAX, measured due to adherence of PAM to the dish, have been compared to values obtained when quartz, coal mine dust (CMD), and kaolin . were added to the medium (in vitro). Rand MAX have also been calculated for PAM lavaged from animals exposed to quartz and CMD in the WVU Inhalation Facility. Presently, experiments are being done using which will permit PAM to be restirnulated by different dusts to help establish a dose response relation~ p and a means to study the role of lung surfactant on modifying the acute toxicity of inbaled dusts. Ultimately, this methodology should provide useful insight into establishing the role of 02 in PAM dysfunction due to inhalation of dusts, and in lung diseases such as pneumoconioses. INTRODOCTIONPAM are free cells found in the lungs which protect the lungs by removing foreign debris and bacteria. This is accomplished, in part, by the process of phagocytosis, whereby foreign matter is internalized into vesicles known as primary phagosomes. Phagocytosis also involves the chemical breakdown of inhaled dusts and the killing of microbes. Detoxification is aided by the respiratory burst, which is a metabolic response of the cell to foreign substances, that results in the production of highly reactive oxidizing agents from the partial reduction of extracellular oxygen to superoxide (02) at the surface of the plasma membrane. Superoxide undergoes either spontaneous or enzyme catalyzed dismutation reactions to form hydrogen peroxide (H202) and subsequently hydroxyl radical (OH•) and singlet oxygen (02 t ). However, while these oxygen metabolites aid in the killing of microbes they also may destroy endogenous tissue. For example, 02 has been linked to the aging process and to many diseases including emphysema, diabetes, and cancer.'' Therefore, a better understanding of the production of 02 is extremely important since an abnonnally low production could result in damage by inhaled dusts and bacteria while an abnormally high production could result in direct damage to the lung tissue by the phagocytes. Inhalation of respirable sized mineral dusts, such as quartz (silica), coal mine dusts (CMD), and asbestos, results in various pulmonary disorders. PAM are thought to play an important role since evidence suggests that the first step in fibrogenesis is an interaction of dust particles with PAM. Generally, in vivo exposure of animals to mineral dusts results in increased respiratory burst activity, migratory patterns, phagocytic behavior, and secretory potential of PAM, and for this reason these have been implicated to be pivotal events in the pathogenesis of pulmonary diseases.1 In addition to stimulation of resident PAM, an influx of monocytes into the lung and/or production of new macrophages generally occurs in response to fibrogenic dust inhalation. Further, PAM may attract and stimulate fibroblasts, which normally synthesize proteins and collagen during rep~ of tissue, by secreting chemoattractants and enzymes. Thus, PAM may be involved in pulmonary disorders through failure or partial loss of their defensive capability, or indirectly, through release of other mediators."

Jan 1, 1990