Search Documents

By E. V. Cilento, K. A. DiGregorio, R. C. Lantz

"DIGREGORIO, K. A., E. V. CILENTO, AND R. C. LANTZ. A kinetic model of superoxide production from single pulmonary alueolar macrophages. Am. J. Physiol. 256 (Cell Physiol. 25): C405-C412, 1989.-A kinetic model was developed to describe the production of superoxide (02) by single pulmonary alveolar macrophages (PAM). Model predictions were compared with experimental results obtained from single rat PAM. The 02 was quantified by measuring the reduction of nitro blue tetrazolium (NBT) to a diformazan precipitate (NBTH,) from video-recorded images of individual cells. The kinetic model considered three reactions: 1 ) the production of extracellular 02 from the reduction of oxygen by NADPH oxidase using intracellular NADPH as the substrate, 2) the subsequent dismutation of 02 to form H,O,, and 3) the reaction of 02 and NBT to form diformazan. NBT specificity for 02 was analyzed by comparing results in the presence and absence of superoxide dismutase (SOD) that catalyzes the dismutation of 02 to H,O,. Measured PAM heterogeneity was accounted for by varying the concentration of intracellular NADPH, its rate of depletion, and the concentration of intracellular NADPH oxidase in the kinetic model. Model predictions compared favorably with experimental results except when SOD was present. This discrepancy may be due to diffusional limitations because NBT is a relatively small molecule (818 mo! wt) compared with SOD (34,000 mol wt). In addition, the cell surface is both ruffled and negatively charged, which may introduce steric hindrances and/ or electrostatic effects, since SOD is also negatively charged, whereas NBT is positively charged.PULMONARY ALVEOLAR MACROPHAGES (PAM) protect the lungs by phagocytizing foreign debris and bacteria. This process is accompanied by the production of superoxide anion (02) at the surface of the plasma membrane (3, 31). Superoxide readily dismutates to form H20 2 and subsequently, other oxygen metabolites which have been shown to be both antibacterial and cytotoxic (21, 25, 35).Superoxide is produced from the reduction of extracellular O, at the surface of the cell membrane by NADPH oxidase by the following reaction (3, 4)"

Jan 1, 1989

By Seong-Taek Lim

Recently, 7xxx aluminum alloys have been evolved into new variants for thick semiproducts which have low amount of 2nd phases and low quench sensitivity. Commercial 7xxx alloys, especially in the thick forgings made of big ingots, often entail microstructural inhomogeneities and concurrent poor mechanical properties due to limited heating ranges and slower quench cooling. In this study, high strength aluminum alloy 7175 and 7050 are adjusted as an attempt to control the equilibrium phases (M-, T- and S-phase) to have optimum microstructure for the thick forging applications. The effects of the relative content of (Zn, Mg, Cu) on the evolutions of the coarse equilibrium phases, hardening response and resultant mechanical properties are investigated. Equilibrium phases (M,T,S) are evolved depending on the constitutional effect, primarily the change of Zn:Mg ratio, and cooling rate following solutionizing. The formation of the T- and S-phases is effectively controlled, and M-phases are homogeneously precipitated in the adjusted (dilute and high Zn:Mg ratio) alloys. It provides extended heating range and lower quench sensitivity than conventional alloys. The attempts ensure the microstructural homogeneity and improved properties, and is expected to be uniquely applicable in 7xxx thick forgings.

Jan 1, 2004

By Alexander L. Peyton

The Magruder and Chambers copper deposits in the Little River gold district, on the border line of Lincoln and Wilkes Counties, Georgia, have been known for a number of years (fig. 1). The Magruder deposit was first opened as a gold mine but has produced mostly copper and load. Records show that about 50 cars of concentrates were shipped from this property. No record of any production at the Chambers deposit is available. The Bureau of Mines, in its program of investigation of strategic minerals deposits, diamond drilled 10 holes, totaling 3,784 feet, on the two properties between December 3, 1948, and June 23, 1949. Eighty-eight core samples were analyzed, and the analyses and drill-hole data are presented in this report.

Jan 1, 1950

By V. Gangrade

Recirculation is the major concern associated with the utilization of booster fans. In controlled recirculation, a portion of the return air is purposely mixed with the intake air and the mixture is directed towards a working district, while the air quantity and gas concentrations in the air are closely monitored and managed. The objectives of this study were to determine the gas concentration in intake and return airways during controlled recirculation, and to determine the recirculation fraction for multiple headings. Experiments were conducted in a laboratory model to determine the effect of controlled recirculation on the quality of air circulated through the working faces. Preliminary results showed that recirculation is beneficial to ventilation planning because it reduces the build-up of air contaminants at the working faces and reduces the overall power consumptions. The experimental results were used to quantify the recirculation fraction and to calibrate ventilation models of the laboratory model. These models are used to simulate the controlled recirculation and to predict the gas concentrations in multiple headings.

Aug 1, 2013

By Monica C. Pinto, Gustavo H. Nalon, José C. L. Ribeiro, Rita de C. S. S. Alvarenga, Leonardo G. Pedroti, Lucas A. F. Fioresi

This study aims to evaluate the influence of mortar’s mechanical properties on the behavior of clay masonry. Experimental studies were performed using prisms of clay blocks under axial compression. The clay units were produced with a clay from Tres Rios, Rio de Janeiro, Brazil and had compressive strength of 4.9 MPa. Two mortar compositions were used, which had compressive strength of 94.7 and 50.4% of the clay blocks’ net area compressive strength. It was noticed a slight increase on the prism’s compressive strength with the increase of the mortars’ compressive strength and stiffness. Prisms made with flexible mortars had a ductile failure and collapsed under lower compressive stresses, while prisms made with stiff mortars resisted higher compressive stresses, but had a brittle failure ,crushing the blocks. A very strong mortar is not recommended. Using more flexibl mortars does not compromise the strength and stiffness of the masonry and prevents an excessively brittle failure of the structure.

Mar 1, 2017

By R Razanatsimba, A Galli

A mining company has entered into contractual commitments to supply certain quantities of its product to clients in each time period. Failure to fulfil its obligations would damage its reputation as a reliable supplier. The planned production would normally be sufficient unless major problems such as highwall failures, roof falls, natural disaster, or strikes that interrupt production or delays in obtaining environmental permits, occur. To overcome these difficulties, the company may be able to obtain more of the commodity: from its strategic stockpile (if there is sufficient there); by buying it on the spot market; or for some commodities such as gold and uranium, by leasing it. Two sources of uncertainty, the spot price of the commodity and the occurrence of serious incidents that interrupt production, are considered. For simplicity it is assumed that the commodity price follows a geometric Brownian motion, that productions incidents have a binomial distribution, that they are independent from one time period to another and that they do not affect prices. A branching tree structure is used to model the joint evolution of prices and production incidents. The aim of this research project was to evaluate the companyÆs options for fulfilling its contractual commitments. When evaluating these options, multi-stage stochastic programming with recourse was used to solve this problem because in addition to providing the dollar value of the project, it gives decision-makers the æroadmapÆ to reach the optimal value. That is, how much material should be bought/sold on the spot market, how much to add to/subtract from the stockpile, how much to lease and in the worst case what the shortfall would be, for each time period as a function of the current spot price and breakdown status. A case-study over a five-year period is used to illustrate the proposed procedure. In this study the production would be sufficient to cover the companyÆs contractual commitments unless production incidents occur. Focus is on evaluating the impact of the quantity initially in the stockpile on the value of the project when the commodity market is tight, that is, when only small quantities can be bought on the spot market or by leasing.

Sep 26, 2011

By Bernard Porter, E. A. Brown

Electrical conductivities and densities of the LiF- UF , LiF- ThF4 , NaF - C1F4 , and NaF - ThF systems were measured as functions of composition and temperature . The specific conductance and density varied linearly with temperature . Molar and equivalent volumes , as well as heats of activation for conductance , were calculated from the experimental data . At 1,000 ° C , the molar volumes ranged from 16 to 40 cubic centimeters per mole and the specific conductance ranged from 9.8 to 2.5 per ohm- centimeter as the actinide metal fluoride concentration changed from 0 to 60 mole - percent . Heats of activation for conductance were 3 to 7 kcal per mole . The data are interpreted on the basis of a semilattice model for the melts .

Jan 1, 1964

By Morgan B. D

Since the mid 1950s, limonite deposits of a new type have been found in the northwest of Western Australia. The deposits consist of extensive fossil valley fillings up to several hundred feet in depth, of medium to high grade limonite, frequently containing limonitized fossil wood, and of Mesozoic or Tertiary age. The distribution of the deposits is closely linked with hilly outcrops of Archaean and Proterozoic jaspilite in the headwaters of the old valleys, from which the iron has been derived by leaching, and presumably re-precipitated by a process not unlike that which operates in forming bog iron deposits. Due to the relative resistance of tlie limonite to erosion, the rejuvenation of streams in the area in recent times has left limonitic remnants as mesas up to· several hundred feet above the levels of the present creeks, the courses of which generally are adjacent to or within a few miles of those of the old limonite filled valleys.The Robe River limonite deposits are the largest of this type known and can be traced for approximately 130 miles along the old stream, over 30 sq. miles of limonite remnants remaining at the present time.The present quantity of limonite in this system alone is probably in excess of 5,000,000,000 tons, and the original quantity must have exceeded four times this tonnage when allowance is made for erosion.Some thousands of millions of tons of this material contain in excess of 54 per cent Fe, with approximately 10 per cent combined water. The chief impurities are SiO2 and Al2O3, and minor elements are not present in objectionable amounts. A portion of these deposits was extensively tested by The Broken Hill Proprietary Company Limited (the B.H.P. Co. Ltd.) during 1962-1964. Most of the data presented in this paper are based on the work done on these deposits which are typical of those discussed. The overall problem of the origin of the limonite is discussed. It is apparent that the limonite originates from the jaspilitesof Archaean and Proterozoic age which form the highlands at the upstream ends of the deposits. The iron oxide has been chemically and/or mechanically derived from these jaspilites and deposited by one or more of the following mechanisms.A.-Chemical-sedimentary mainly by biological agenciesB.-Replacement of fluviatile sediments by iron-charged watersC.-Clastic sedimentary processesD.-Lateritization of fluviatile sediments.These various mechanisms are discussed; the authors favour machanismA.Manuscript received' at The Institute, 14th July, 1964.

Jan 1, 1964

By Charles H. Morgan

THE case of Henry Cort comprises: (1) the nature of Cort's inventions;, (2) their value to England and to mankind,; (3) the remuneration received therefor by him or his family; and (4) the suitable permanent record and recognition of his services by the representatives of the art lie founded-a debt long over-due, and still unpaid. I. CORT'S INVENTIONS. Under this head, it is unnecessary here to enter into details. The facts have been repeatedly published, and a brief outline of them will be sufficient for my present purpose. . Henry Cort, born in 1740 at Lancaster, England, became a navy broker in. London about 1765, and gained from that business in about ten years. something more than £20,000, which lie devoted to perfecting the manufacture of iron, building a mill at Fontley, near Portsmouth, and prosecuting, between 1777 and 1783, the experiments which culminated in .his two patents, one for puddling iron and the other for shaping it by rolling between grooved rolls.: Careful study of the contemporary evidence, including Cort's specifications, the testimony (in act as well as word) of his business rivals, the public declarations of eminent authorities, and the history of the times, leaves no possible doubt that Cort was the real inventor, of

Mar 1, 1905

By J. B. Hanlon

In order to protect coal mine owners, operators, and lending institutions from potential environmental liabilities, responsible parties must maintain a thorough understanding of the environmental disposition of the property they control, and the ramifications of impending laws and regulations. The best way to accomplish this is to periodically conduct a Phase I Environmental Audit. The systematic approach of an audit will reveal areas of DOD compliance with SMCRA and EPA regulations which the coal owner and/or operator will be able to use to correct deficiencies and prevent the occurrence of conditions which could lead to permit block, fines, and ultimately reduced productivity.

Jan 1, 1995

By H. H. Schrenk

The purpose of respiratory protective equipment is to prevent the inhalation of harmful or objectionable atmospheres. Although constituents or contaminants that may render an atmosphere irrespirable or objectionable are numerous, they may be classified broadly as follows: I. Gaseous substance: n. A. Toxic. B. Inert (oxygen deficiency). II. Particulate matter (dispersoids). A. Solid. a. Dust (formed by disintegration). b. Pure (formed by condensation). B. Liquid. a. Mist (formed by disintegration). b. Fog (former by condensation).

Jan 1, 1940

By Thomas M. Barczak

The resultant load vector is the representation of the forces applied to a longwall roof support element by caving strata into a single, quantifiable measure of support resistance. The relatively complex kinematics of the shield support prohibit a determination of support resistance simply by summation of leg forces. A method is being investigated by the Bureau of Mines to determine the resultant load vector by instrumenting supports with pressure transducers and strain gages to measure leg, canopy capsule, and lemniscate link forces. This concept has been laboratory tested in the Bureau's Mine Roof Simulator. Functional relationships among variables have been assessed, and confidence intervals have been established for prediction of the resultant load vector parameters.

Jan 1, 1984

By Joel Lenz, Warren Hood, Jackson Jenkins

Whole ore or other process streams are being transported from mines to remote processing facilities for multiple reasons, such as improved project economics, maximum utilization of capital, and minimization of environmental risk. Case studies will be presented from a variety of operations. Glenbrook Nickel processes ore from their deposit and receives ore from New Caledonia, crushes and dries the ore, and transports it inland to the smelter. The Mule Canyon and Rosebud ore bodies truck-haul their ores to the Lone Tree and Twin Creeks processing plants. Pegasus Gold hauls their Diamond Hill ore to their Montana Tunnels facilities, and Sierrita pumps solution to an existing tank house 8 miles away for electrolytic recovery.

Jan 1, 1998

By Stephen J. Crittenden

Deep gas and oil production has been substantially increased over prolonged periods through the use of sintered bauxite propping agents. Since its inception in 1976, over 170,000,000 pounds of high strength ceramic proppants have been employed. Recent field evaluations and economic analysis demonstrate the superiority of sintered bauxite proppant over quartz sand. This paper describes the development, application, field results, and product evolution of sintered bauxite.

Jan 1, 1983

By John A. Johnson

"INTRODUCTION The use of wet drilling with adequate ventilation has largely controlled production of dust in drilling rock; however, in some operations, such as shaft sinking and modern tunnel driving, when each of a number of drills is operating in a small cross-sectional area, it is at times difficult to ventilate well enough to keep the dust concentration within desired limits.Some chemical compounds, known as wetting agents, when added to water in small quantities reduce the interfacial tension and make it possible for the solution to wet dust particles more effectively than water alone.This report presents results of tests on the effectiveness of two wetting solutions in reducing the amount of dust produced by wet drilling in basalt.ACKNOWLEDGMENTSThe tests were conducted the Bureau's Mount 'Weather Testing Adit,Mount Weather, The author acknowledges the assistance and cooperation of Wing G. Agnew, superintendent; Marvin M. Revelle, mining-engineering aide; and the rest of the crew at Mount Weather in conducting the tests. C. W. Owings, mining engineer, Safety Division, assisted in conducting some of the first tests and gavel valuable advice and guidance throughout the work and in preparing this report."

Jan 1, 1943

By MAURICE SUNKPAL, Taghi Sherizadeh, Kutay E. Karadeniz, Dogukan Guner, Samuel Nowak

Despite numerous empirical, numerical, and hybrid studies conducted on the subject of coal rib failure, mine fatalities related to rib failures continue to occur at around 1.5 per year between 2009 and 2021. To date, a standard methodology for the design of coal rib supports that can accommodate the wide range of unique conditions found in coal mines in the USA has not been developed, forcing mine operators to rely on the trial-and-error process or industrial legacy practices for the design of coal rib support patterns. In this study, to better understand the support systems’ effectiveness, various rib bolting scenarios were investigated. A coal mass constitutive model is implemented to a distinct element method (DEM) code, and rib factor-of-safety (RibFOS) analyses were performed by applying strength-reduction for the coal matrix and explicitly modeled face cleats. Ribs with various overburden depths and mining heights composed of solid Banded-Bright coal (BBC) were considered in this study. Different scenarios such as rib bolt length and the number of bolts were studied to quantify the effect of primary rib support density on rib stability. As a result of the unsupported coal rib analyses, a decaying exponential relationship is proposed between the mining height-overburden depth and the RibFOS. The developed coal rib models clearly show the coal-rib bolt interaction and illustrate how the addition of rib bolts restricts the movement of the coal rib. The results reveal that the strength reduction method in DEM code with the coal-mass model can aid in the development of practical primary support charts, which can help in the rib support design process. In addition, an unsupported RibFOS cutoff is proposed, beyond which the addition of primary support cannot stabilize the failed rib structure.

Aug 5, 2023

By Jan M. Mutmansky

Simulation is a general term which commonly appears in the technical literature and which can have different meanings to different people. One interesting definition (9)* applicable in an engineering context is the following: "Simulation is the use of a model to study a problem." In most cases, the model referred to in the above definition is a simulation model constructed in a computer language and implemented on a computer in order to solve the problem under consideration. The application of computer simulation models to the study of problems in materials handling and earthmoving has been successful in the past. Generally speaking, this method has been used where the system to be studied has many variables and where the ability to predict the outcome of the system under different sets of conditions is difficult. The prime reason for using such a model is to evaluate the numerous likely ways of operating any particular system without the necessity of actually conducting full-scale field tests. The simulation model presented here is such an application made to the process of tunneling and, in particular, to the process of tunneling with a boring-type tunneling device. At first glance, the process of tunneling may not appear to be particularly complex and susceptible to study by a computer model. However, a close analysis of the tunneling process will reveal that it is rather complicated as a result of limitations placed upon the system by restricted space in the tunnel, geologic variations along the tunnel

Jan 1, 1972

"NI 43-101 is a rule that governs how issuers disclose scientific and technical information about mineral projects to the public in Canada. The disclosure standards apply to oral statements as well as written documents and websites. NI 43-101 does not apply to disclosure concerning petroleum, natural gas, bituminous sands or shales, groundwater, or coal be methane. NI 43-101 first came into force on Feb. 1, 2001 and was revised in December 30, 2005. As a “National Instrument”, the law has been passed in each provincial and territorial legislature across Canada.“PART 1 DEFINITIONS AND INTERPRETATION 1.1 Definitions - In this Instrument “adjacent property” means a property(a) in which the issuer does not have an interest;(b) that has a boundary reasonablyproximate to the propertybeing reported on; and (c) that has geological characteristics similar to those of the property being reported on; “data verification” means the process of confirming that data has been generated withproper procedures, has been accurately transcribed from the original source and is suitable to be used; “development property” means a property that is being prepared for mineral production and for which economic viability has been demonstrated by a feasibility study; “disclosure” means any oralstatement orwritten disclosure made by oron behalf of an issuer and intended to be, orreasonablylikely to be, made available to the public in a jurisdiction of Canada, whether or not filed under securitieslegislation, but does not include written disclosure that is made available to the public only by reason of having been filed with a government or agencyof government pursuant to a requirement of lawother than securities legislation; “early stage exploration property” means a property that has(a) no current mineral resources or mineral reserves defined; and (b) no drilling or trenching proposed; in a technical report being filed in a local jurisdiction; “exploration information” means geological, geophysical, geochemical, sampling, drilling, trenching, analytical testing,assaying, mineralogical, metallurgical and other similar information concerning a particular property that is derived fromactivities undertaken to locate, investigate, define or delineate a mineral prospect or mineral deposit; “feasibility study” means a comprehensive studyof a mineral deposit in which all geological, engineering, legal,operating, economic, social, environmental and other relevant factors are considered in sufficient detail that it could reasonably serve as the basis for a final decision by a financial institution to finance the development of the deposit for mineral production; “historical estimate” means an estimate of mineral resources or mineral reserves prepared prior to February 1, 2001;“IMMM Reporting Code” means the classification system and definitions of mineral resources and mineral reservesapproved by The Institution of Materials, Minerals, and Mining in the United Kingdom, as amended; “JORC Code”means the Australasian Code for Reporting of Mineral Resources and Ore Reserves prepared by the Joint Ore Reserves Committee of the Australasian Institute of Mining and Metallurgy, Australian Institute ofGeoscientists and Mineral Council of Australia, as amended; “mineral project” means any exploration, development or production activity, including a royalty interest or similarinterest in these activities, in respect of diamonds, natural solid inorganic material, or natural solid fossilized organic material including base and precious metals, coal, and industrial minerals;"

Jan 1, 2003

By A. C. Atenas

The majority of refineries that operate with traditional starting sheet technology ?starting sheet- uses a relatively low current density of 250 A/m2. Industrial tests at high current density with conventional technology were carried out in Refinery of Potrerillos, getting satisfactory results that are similar the results obtained with permanent cathode technology. The series of copper refining electrolyses electrolysis trials were carried out between 300 to 325 A/m2. Electrolysis conditions, in accordance with industrial practice, were kept constant in all sets of experiments and were as follows; 45 g/L Cu 2+, 210 g/L H2SO4, 62 °C, electrolyte circulation of 14-18 L/min. The same Dosing dosing of Additives additives used in permanent cathode technology was required in these tests. In general, only not importantminor operational modifications were necessary in comparison to normal practice in the Refinery to assure the good results. Different quality of starting sheet and anodes were examined. The test included starting sheets from smelter and laminated process. Results indicate that the charge physical quality of the electrodes and the control of the process during the two first days of operation are the keys to get the best results.

Jan 1, 2007

By Seth T. Reese

THE INJURY DATA and experience at coal mines in the United States for 1949 are presented in this bulletin under the following general sections: (A) General injury experience: 1. Tables 1 to 18: Contain current data on number of injuries, frequency and severity rates, average severity, major and detailed classification of injuries, and distribution of injuries by part of body and days of disability. (B) Selected injury data: 1. Tables 19 to 45: Contain current data on various selected factors of operating and physical conditions that have contributed to the occurrence of injuries at bituminous-coal mines and at Pennsylvania anthracite mines. These factors include extent of hand and machine loading, size of mine by employment and production groups, thickness of bed or vein, duration and number of work shifts, rating of mine as gassy, or nongassy, types of cap lamps, ventilation, explosives, and combinations of factors that influence mine safety. (C) Injury experience by States: 1. Tables 46 to 52: Contain current data on number of injuries, frequency and severity rates, average severity, major classification of injuries, injury records of all coal-producing States, and the relative standing by States according to injury-frequency rates. (D) Appendix: 1. Tables 53 to 84: Contain certain injury data for the years 1943-47 that have not heretofore been published.

Jan 1, 1953